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Genomics
Written primarily for 16-19 year old students, this primer aims to extend students' knowledge and inspire them to take their school-level learning further.It explores topics that are familiar from the curriculum and also introduces new ideas, giving students a first taste of the study of biology beyond school-level and demonstrating how concepts frequently encountered at school are relevant to and applied in current research.This is the ideal text to support students who are considering making the transition from studying biology at school to university. This Oxford Biology Primer will introduce students to the field of genomics and its applications.From the early days of the Human Genome Project, sequencing technology has rapidly developed and is now cheaper and more accessible than ever before.The resulting pervasive nature of these technologies make them more likely to be experienced by people as patients, consumers and citizens. The primer introduces the basic principles of genomics and then uses these to consider human genetics, through examples of some of the rare diseases linked to single genes.The impact of these rare diseases is far-reaching and the knowledge gained through genome sequencing is proving invaluable in their diagnosis.Genome sequencing is revolutionising the diagnosis and treatment of cancer, and the primer introduces students to some of the key breakthroughs which have taken place in recent years.These include the identification of specific genes indicating cancer risk, and the sequencing of tumours throughout treatment to identify further mutations and modify treatment accordingly. The primer aims to address a number of the ethical issues which are raised by this rapidly-growing area of biology.Students are challenged to consider some of the decisions they may need to make relating to these technologies in their own lives, and are given opportunities to explore different aspects of these issues in a way which allows discussion to be both informed and meaningful. The study of infectious disease is also feeling the impact of genomics: the primer discusses the concept of pathogen genome sequencing, and illustrates the various ways in which this can be used - for example, enabling us to find different solutions to infections, to track outbreaks of disease to their source, and to identify and possibly ultimately combat antibiotic resistance. Many of the major diseases which impact the global population are caused by parasites, which come in a wide variety of shapes and sizes.The primer introduces students to the importance of understanding parasite genomes.Parasite genome sequencing makes it possible to develop both new medicines, and new treatments such as gene drive systems to wipe out disease-causing mosquito populations. For many years, our views of classification and evolution have been based on observational techniques going back to Darwin and Linnaeus.Focusing on human evolution, the primer will open students' eyes to the ways in which genome sequencing is being used to reveal evolutionary links that have never before been recognised, and to elucidate the way humans spread out of Africa across the world.Students are not always aware of the role technological developments play in enabling the progress of science.The final chapter delves into how genome sequencing technologies have developed, considering both the speed of change in the technology, its implications for usefulness, availability and cost, and the growing issue of big data and how it can be manipulated.The different technologies described in this chapter are referenced throughout the book.
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Plant Genomics
Introduction to the range of molecular techniques to investigate unique facets of plant growth, development, and responses to the environment Plant Genomics introduces the complex relationship between the genome, microbiome, genes, and epigenetics of plants, as well as the range of molecular techniques applicable to investigating the unique facets of plant growth, development, and response to the environment.State-of-the-art science in the field is discussed, as well as future outlooks on what the next decade is likely to bring.This book includes new techniques for modifying the plant genome and their impact on modifying plants to combat the impact of biotic and abiotic stresses, including those associated with climate change, new technologies including long and short read sequencing and proximity ligation and the combination of these technologies for assembling sequence data into chromosomes, a new chapter on the sequences of the chloroplast and mitochondrial genomes, and a dedicated chapter to epigenetics and the importance in gene regulation.Written by a highly qualified author with significant published research contributions to the field, Plant Genomics includes information on: Structure and information content of the chloroplast and mitochondrial genomes and their use in phylogenyUse of transcriptomes from various tissues to identify expressed sequences and their identification as genesFunction of small regulatory RNAs and long non-coding RNAs and involvement of small RNAs in the control of gene expressionEpigenetic silencing of transposable elements and their release by stress and cross-generational contribution of epigenetic variationUse of the pan-genome to assemble a comprehensive germplasm for a particular crop species Plant Genomics is an ideal textbook for undergraduate courses on plant biology, particularly those focusing on molecular descriptions, and a helpful auxiliary text to plant biology laboratory courses.It will also be of interest to students in plant molecular biology, agricultural and food sciences, and plant, food, and crop bioengineering.
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Introduction to Genomics
Our genome is the blueprint for our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism.Yet it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on and off in many combinations to give the variety of cells from which our bodies are formed.But how do we identify the genes that make up our genome?How do we determine their function? And how do different genes form the regulatory networks that direct the processes of life?Introduction to Genomics is the most up-to-date and complete textbook for students approaching the subject for the first time.Lesk's engaging writing style brings a narrative to a disparate field of study and offers a fascinating insight into what can be revealed from the study of genomes.The book covers: the similarities and differences between organisms; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing.The Online Resource Centre accompanying Introduction to Genomics features: For students: - Extensive and imaginative weblems (web-based problems) for each chapter designed to give you practice with the tools required for further study and research in the field- Hints and answers to end-of-chapter problems and exercises support your self-directed learning- Guided tour of websites and major archival databanks in genomics offer a wealth of resources to springboard your own research - Journal club: links to related research articles on topics covered in the book are paired with engaging questions to improve your interpretation of the primary literature- Rotating figures allow you to visualize complex structuresFor registered adopters: - Downloadable figures from the book.
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Introduction to Genomics
Our genome is the blueprint for our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism.Yet it is more than a static information store: our genome is a dynamic, tightly regulated collection of genes, which switch on and off in many combinations to give the variety of cells from which our bodies are formed.But how do we identify the genes that make up our genome?How do we determine their function? And how do different genes form the regulatory networks that direct the processes of life?Introduction to Genomics is the most up-to-date and complete textbook for students approaching the subject for the first time.Lesk's engaging writing style brings a narrative to a disparate field of study and offers a fascinating insight into what can be revealed from the study of genomes.The book covers: the similarities and differences between organisms; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing. Digital formats and resourcesThe book is available for students and institutions to purchase in a variety of formats, and is supported by online resources:· The e-book offers a mobile-compatible experience and convenient access along with functionality tools, navigation features, and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks· Online resources, available for registered adopters, include downloadable figures and tables from the book· E-book and Trove formats are enriched with online resources for students, including extensive and imaginative weblems (web-based problems) for each chapter; hints and answers to end-of-chapter problems and exercises to support self-directed learning; a guided tour of websites and major archival databanks in genomics to springboard further research; Journal Club (links to related research articles on topics covered in the book paired with engaging questions); and rotating figures which allow readers to visualize complex structures.
Price: 49.99 £ | Shipping*: 0.00 £
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Are there wireless bodysuits for lingerie?
Yes, there are wireless bodysuits available for lingerie. These bodysuits are designed to provide comfort and support without the need for traditional underwire. They are often made with soft, stretchy materials and seamless construction to create a smooth and flattering silhouette. Wireless bodysuits are a popular choice for those looking for a more comfortable and natural feel while still enjoying the benefits of shaping and support.
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What is Western riding apparel?
Western riding apparel refers to the clothing and accessories worn by riders in Western-style horseback riding. This typically includes a cowboy hat, long-sleeved shirt, jeans, cowboy boots, and a belt with a buckle. Western riding apparel is designed to be practical and comfortable for the rider while also reflecting the traditional Western cowboy aesthetic. Additionally, riders may also wear chaps, spurs, and gloves as part of their Western riding attire.
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What is western riding apparel?
Western riding apparel refers to the clothing and gear worn by riders who participate in western-style horseback riding. This typically includes a cowboy hat, long-sleeved shirt, jeans, cowboy boots, and a belt with a western-style buckle. Additionally, riders may wear chaps, spurs, and gloves for added protection and functionality. The apparel is designed to be comfortable, durable, and practical for the demands of western riding disciplines such as trail riding, ranch work, and rodeo events.
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Can regular bodysuits be converted into thong bodysuits?
Regular bodysuits can potentially be converted into thong bodysuits by altering the bottom portion of the garment. This would involve cutting away the fabric at the back to create a thong-style bottom, as well as potentially adjusting the fit and design of the bodysuit to accommodate this change. However, it is important to note that the success of this conversion would depend on the original construction of the bodysuit and the skills of the person attempting the alteration.
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Computational Genomics with R
Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics.The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques.The text provides accessible information and explanations, always with the genomics context in the background.This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented.As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds.For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology.After reading:You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin.He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002.He has published an extensive body of work in this area.The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.
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Data Science for Genomics
Data Science for Genomics presents the foundational concepts of data science as they pertain to genomics, encompassing the process of inspecting, cleaning, transforming, and modeling data with the goal of discovering useful information, suggesting conclusions and supporting decision-making.Sections cover Data Science, Machine Learning, Deep Learning, data analysis, and visualization techniques.The authors then present the fundamentals of Genomics, Genetics, Transcriptomes and Proteomes as basic concepts of molecular biology, along with DNA and key features of the human genome, as well as the genomes of eukaryotes and prokaryotes. Techniques that are more specifically used for studying genomes are then described in the order in which they are used in a genome project, including methods for constructing genetic and physical maps.DNA sequencing methodology and the strategies used to assemble a contiguous genome sequence and methods for identifying genes in a genome sequence and determining the functions of those genes in the cell.Readers will learn how the information contained in the genome is released and made available to the cell, as well as methods centered on cloning and PCR.
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Bacterial Genetics and Genomics
Understanding of bacterial genetics and genomics is fundamental to understanding bacteria and higher organisms, as well.Novel insights in the fields of genetics and genomics are challenging the once clear borders between the characteristics of bacteria and other life.Biological knowledge of the bacterial world is being viewed under a new light with input from genetic and genomics.Replication of bacterial circular and linear chromosomes, coupled (and uncoupled) transcription and translation, multiprotein systems that enhance survival, wide varieties of ways to control gene and protein expression, and a range of other features all influence the diversity of the microbial world.This text acknowledges that readers have varied knowledge of genetics and microbiology.Therefore, information is presented progressively, to enable all readers to understand the more advanced material in the book. This second edition of Bacterial Genetics and Genomics updates the information from the first edition with advances made over the past five years.This includes descriptions for 10 types of secretion systems, bacteria that can be seen with the naked eye, and differences between coupled transcription-translation and the uncoupled runaway transcription in bacteria.Topic updates include advances in bacteriophage therapy, biotechnology, and understanding bacterial evolution. Key FeaturesGenetics, genomics, and bioinformatics integrated in one placeOver 400 full-colour illustrations explain concepts and mechanisms throughout and are available to instructors for downloadA section dedicated to the application of genetics and genomics techniques, including a chapter devoted to laboratory techniques, which includes useful tips and recommendations for protocols, in addition to troubleshooting and alternative strategiesBulleted key points summarize each chapterExtensive self-study questions related to the chapter text and several discussion topics for study groups to explore furtherThis book is extended and enhanced through a range of digital resources that include:Interactive online quizzes for each chapterFlashcards that allow the reader to test their understanding of key terms from the bookUseful links for online resources associated with Chapters 16 and 17
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Bacterial Genetics and Genomics
Understanding of bacterial genetics and genomics is fundamental to understanding bacteria and higher organisms, as well.Novel insights in the fields of genetics and genomics are challenging the once clear borders between the characteristics of bacteria and other life.Biological knowledge of the bacterial world is being viewed under a new light with input from genetic and genomics.Replication of bacterial circular and linear chromosomes, coupled (and uncoupled) transcription and translation, multiprotein systems that enhance survival, wide varieties of ways to control gene and protein expression, and a range of other features all influence the diversity of the microbial world.This text acknowledges that readers have varied knowledge of genetics and microbiology.Therefore, information is presented progressively, to enable all readers to understand the more advanced material in the book. This second edition of Bacterial Genetics and Genomics updates the information from the first edition with advances made over the past five years.This includes descriptions for 10 types of secretion systems, bacteria that can be seen with the naked eye, and differences between coupled transcription-translation and the uncoupled runaway transcription in bacteria.Topic updates include advances in bacteriophage therapy, biotechnology, and understanding bacterial evolution. Key FeaturesGenetics, genomics, and bioinformatics integrated in one placeOver 400 full-colour illustrations explain concepts and mechanisms throughout and are available to instructors for downloadA section dedicated to the application of genetics and genomics techniques, including a chapter devoted to laboratory techniques, which includes useful tips and recommendations for protocols, in addition to troubleshooting and alternative strategiesBulleted key points summarize each chapterExtensive self-study questions related to the chapter text and several discussion topics for study groups to explore furtherThis book is extended and enhanced through a range of digital resources that include:Interactive online quizzes for each chapterFlashcards that allow the reader to test their understanding of key terms from the bookUseful links for online resources associated with Chapters 16 and 17
Price: 130.00 £ | Shipping*: 0.00 £
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How can one use underwear as loungewear?
Underwear can be used as loungewear by choosing comfortable and breathable styles such as boyshorts, briefs, or bralettes. Pairing them with a loose-fitting tank top or oversized t-shirt can create a relaxed and casual loungewear look. Additionally, layering a cozy robe or cardigan over the underwear can add extra comfort and warmth. It's important to choose underwear made from soft and stretchy fabrics to ensure maximum comfort while lounging.
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When do you wear bodysuits?
I wear bodysuits when I want a sleek and seamless look, such as when I'm wearing high-waisted pants or skirts. Bodysuits are also great for layering under sheer or low-cut tops, providing a polished and put-together look. Additionally, I wear bodysuits for dance or exercise activities, as they provide a secure and comfortable fit.
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Are there bodysuits without bottoms?
Yes, there are bodysuits without bottoms. These types of bodysuits typically cover the upper body and have a thong or G-string style bottom, leaving the lower half of the body exposed. They are often worn with skirts, pants, or shorts to create a seamless and sleek look. These bodysuits are popular for their versatility and ability to provide a smooth, tucked-in appearance without the need for tucking in a shirt.
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How do you wear bodysuits?
Bodysuits can be worn in a variety of ways depending on personal style and the occasion. They can be paired with high-waisted jeans or skirts for a casual look, or with dress pants or a skirt for a more formal outfit. Some people like to layer bodysuits under jackets or blazers for a chic and polished look. Additionally, bodysuits can also be worn on their own with accessories like statement jewelry or a belt to add some flair to the outfit.
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